DEVELOPMENT AND VALIDATION OF VECTORS CONTAINING MULTIPLE SIRNA EXPRESSION CASSETTES FOR MAXIMIZING THE EFFICIENCY OF GENE SILENCING

Development and validation of vectors containing multiple siRNA expression cassettes for maximizing the efficiency of gene silencing

Abstract Background RNA interference (RNAi) was originally identified as a biological process in which short double-stranded RNA (dsRNA) suppress the expression of genes complimentary to the dsRNA.This cellular intrinsic gene silencing mechanism has subsequently been developed as a ORG STEVIA TOFFEE useful tool for studies of gene function.A major

read more

Newly Identified Deficiencies in the Multiple Sclerosis Central Nervous System and Their Impact on the Remyelination Failure

The pathogenesis of multiple CRANBERRY sclerosis (MS) remains enigmatic and controversial.Myelin sheaths in the central nervous system (CNS) insulate axons and allow saltatory nerve conduction.MS brings about the destruction of myelin sheaths and the myelin-producing oligodendrocytes (ODCs).The conundrum of remyelination failure is, therefore, cruc

read more